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2013年9月24日星期二

List of 45 Medications that Cause Unusual Dreams



In the last decade or so, “unusual dreams” has cropped up more and more as a normal side effect of perscription medications.  These tend to be medications somehow effect brain chemistry, such as some antidepressants.  It is unknown if these drugs cause the unusual dream or just makes you more aware of your dreams.


If you suspect that your meds are giving you nightmares, don’t just stop cold turkey.  This can cause dangerous or painful withdrawal symptoms — not to  mention the return of the symptoms you were trying to avoid in the first place.  Talk to your doctor first about tapering off.


Here is an incomplete alphabetical list of perscription medications that give you unusual dreams or nightmares.  Check out this list from NBC affiliate Channel 3 WYKC (taken from a Wall Street Journal article but my computer downloads it faster than WSJ, so there) Here’s another list by pharmacist Suzy Cohen:





  1. Adderall (amphetamine and dextroamphetamine): treats ADHD and may cause nightmares


  2. Albuterol sulfate: Asthma medication that apparently has nightmares as a very rare side effect.


  3. Ambien (zolpidem sulfate): Heavily perscribed insomnia drug known to cause sleepwalking, sleep driving and bad dreams.


  4. Amphetamine: Used to treat narcolepsy and ADD reported to help with lucid dreams and vivid dreams.


  5. Aricept (donepezil): Medication for sleep apnea in Alzheimer’s patients and dementia that seems to help patients remember their dreams and anectodal reports states it causes bizarre dreams.


  6. Atenolol: A beta blocker known to cause bad dreams as noted in this 1985 study.


  7. Atripla (Efavirenz/Emtricitabine/Tenofovir): An AIDS drug that contains sustiva, so see Sustiva.


  8. Avelox (moxifloxacin): An antibiotic that has at least 66 complaints of bad dreams to the FDA.  It is an uncommon side effect.


  9. Betaxolol:


  10. Biaxin (Clarithromycin): An antibiotic that has at least 12 complaints of bad dreams to the FDA.  It is an uncommon side effect.


  11. Bisoprolol Fumarate: Another beta blocker known to cause vivid dreams.


  12. Bystolic (nebivolol): Yet another beta blocker that sometimes causes “weird/vivid dreams.”


  13. Carbidopa: See Levodopa


  14. Carvedilol: Another beta blocker, etc


  15. Chantix (varenicline): This is perscriped to smokers to help them quit.  The manufacturer claims that Chantix blocks nicotene receptors in the brain so that a smoker does not receive the same amount of pleasure smoking.  The Internet is loaded with anectodal weird and bad dreams that patients claim to have experiences while taking Chantix.  “Changes in dreaming” is one of the most common complaints about Chantix.


  16. Cipro (ciprofoxacin): An antibiotic where “nightmares or abnormal dreams” is a side effect listed as serious enough to warrant telling your doctor.


  17. Coreg (carvedilol): Another beta blocker that can cause strange dreams.


  18. Cymbalta (duloxetine): An SSRI antidepressant where scary or weird dreams is a common side effect.


  19. Depakote (divalproex sodum): A seizure drug often perscribed for people wuffering from migraines.  An uncommon side effect is abnormal dreams.


  20. Dramamine (Dimenhydrinate): This is an over the counter (OTC) drug for motion sickness that some people claim causes nightmares.  Never did for me, though.  This is a rare side effect.


  21. Effexor (venlafaaxine): An SSRI antidepressant where scary or weird dreams is a common side effect, according to this study.


  22. Labetalol: A common beta blocker that sometimes causes nightmares or strange dreams.


  23. Lamictal (lamotrigine): An anti-seizure medication that tries to “reduce abnormal brain activity.”  Weird dreams are a common side effect.


  24. Levaquin (levafloxacin): Another antibotic known to sometimes cause nightmares or abnormal dreams.


  25. Levodopa:  This is used to treat Parkinson’s disease.  Bad dreams are common when on this drug.  A 1978 study noted that about 30% of patients studied reported bad dreams.  This happened with and without the patient also taking carbidopa.


  26. Lexapro (escitoprolam):  Another SSRI antidepressant where bad or unusual dreams are common side effects.


  27. Metoprolol: Another betab locker known to sometimes cause “strange dreams.”


  28. Nadolol: Another beta blocker, etc.


  29. Nebivolol: Another beta blocker, etc


  30. Nicotene transdermal patches: OTC smoking cessation device is thought to cause unusual dreams in this 2006 study.


  31. Paxil (paroetine): GlaxoSmithKlein’s SSRI antidepressant noted for causing suicidal behavior in some young patients.  So, if a get nightmares while taking it, consider yourself lucky.  You’re still alive. Uusually, doctors will try a “softer” antidepressant like Prozac before trying Paxil.


  32. Pindolol: Another beta blocker, etc


  33. Prazosin: Blood pressure medication thought to decrease nightmares in PSTD sufferers.


  34. Propranolol: Another common beta-blocker (sometimes perscribed off label for migraines) that can cause nightmares or vivd dreams.


  35. Prozac (fluoextine): Perhaps the most perscribed drug in the world, this SSRI antidepressant has been known to cause unusual dreams.  (Not with me, though.)


  36. Ritalin (Methylphenidate): Yeah, THAT Ritalin.  Thought to cause nightmares.


  37. Straterra (atomoxetine hydrochloride): Medication for AD/HD reportedly can cause nightmares.


  38. Sustiva (efavirenz): Used to treat AIDS and thought to cause nightmares.  I’d think the nightmares would be a relief, quite frankly.


  39. Tamiflu (Oseltamivir): Treats influenza in children butuk  researchers note that it can sometimes cause nightmares.


  40. Topamax (topiramate): Medication for migraines and epilepsy sometimes linked to nightmares.


  41. Wellbutrin (bupropion): Yet another SSRI antidepressant linked to bad dreams and nightmares.


  42. Xanax (alprazolam): Bad and vivid dreams are a very uncommon side effect for this anti-anxiety medication. I did have bad dreams when on Xanax, but I have bad dreams seemingly every night.


  43. Zocor (simvastatin): A common statin which can helps lower blood pressure but also cause nightmares and abnormal dreams.


  44. Zoloft/Lustrene (sertraline hydrochloride): A common SSRI antidepressant used for a variety of psychological conditions and some off-label ailments, including menopause and some heart conditions.  Sometimes the dreams are described as “vivid” which I’m not sure is a bad thing.  This 1999 study looked at one woman taking Zoloft who had dreams of being attacked.  That’s a bad thing.


  45. Zyban (bupropion) : See Wellbutrin


2013年9月23日星期一

Drug Information Update - New safety requirements for long-acting inhaled asthma medications called Long-Acting Beta-Agonists (LABAs)



Drug Information Update – New safety requirements for long-acting inhaled asthma medications called Long-Acting Beta-Agonists (LABAs)


The Division of Drug Information (DDI) is CDER’s focal point for public inquiries. We serve the public by providing information on human drug products and drug product regulation by FDA.


Due to safety concerns, the U.S. Food and Drug Administration (FDA) is requiring changes to how long-acting inhaled medications called Long-Acting Beta-Agonists (LABAs) are used in the treatment of asthma. These changes are based on FDA’s analyses of studies showing an increased risk of severe exacerbation of asthma symptoms, leading to hospitalizations in pediatric and adult patients as well as death in some patients using LABAs for the treatment of asthma.


LABAs are approved as single-ingredient products (Serevent and Foradil) and as an ingredient in combination products containing inhaled corticosteroids (Advair and Symbicort) for the treatment of asthma and chronic obstructive pulmonary disease (COPD). They work by relaxing muscles in the airway and lungs. This helps patients breath easier, and lessens symptoms such as wheezing and shortness of breath. The new recommendations only apply to the use of LABAs in the treatment of asthma.


For more information, please visit: LABAs
http://www.fda.gov/Drugs/DrugSafety/PostmarketDrugSafetyInformationforPatientsandProviders/ucm200776.htm


FDA Drug Safety Communication: New safety requirements for long-acting inhaled asthma medications called Long-Acting Beta-Agonists (LABAs)


Safety Announcement
Additional Information for Patients
Additional Information for Healthcare Professionals
FDA Approved Medications Containing a Long-Acting Beta Agonist (LABA)
Data Summary


Safety Announcement
[02-18-2010] Due to safety concerns, the U.S. Food and Drug Administration (FDA) is requiring changes to how long-acting inhaled medications called Long-Acting Beta-Agonists (LABAs) are used in the treatment of asthma. These changes are based on FDA’s analyses of studies showing an increased risk of severe exacerbation of asthma symptoms, leading to hospitalizations in pediatric and adult patients as well as death in some patients using LABAs for the treatment of asthma (see Data Summary below).
LABAs are approved as single-ingredient products (Serevent and Foradil) and as an ingredient in combination products containing inhaled corticosteroids (Advair and Symbicort) for the treatment of asthma and chronic obstructive pulmonary disease (COPD). They work by relaxing muscles in the airway and lungs. This helps patients breath easier, and lessens symptoms such as wheezing and shortness of breath. The new recommendations only apply to the use of LABAs in the treatment of asthma.
To ensure the safe use of these products:
The use of LABAs is contraindicated without the use of an asthma controller medication such as an inhaled corticosteroid. Single-ingredient LABAs should only be used in combination with an asthma controller medication; they should not be used alone.
LABAs should only be used long-term in patients whose asthma cannot be adequately controlled on asthma controller medications.
LABAs should be used for the shortest duration of time required to achieve control of asthma symptoms and discontinued, if possible, once asthma control is achieved. Patients should then be maintained on an asthma controller medication.
Pediatric and adolescent patients who require the addition of a LABA to an inhaled corticosteroid should use a combination product containing both an inhaled corticosteroid and a LABA, to ensure compliance with both medications.
FDA is also requiring a risk management program called a Risk Evaluation and Mitigation Strategy (REMS) for these products. The REMS for LABAs will include a revised Medication Guide written specifically for patients, and a plan to educate healthcare professionals about the appropriate use of LABAs. In addition, FDA is requiring the manufacturers to conduct additional clinical trials to further evaluate the safety of LABAs when used in combination with inhaled corticosteroids. FDA will seek input on these studies at a public advisory committee meeting on March 10-11, 2010.
FDA has determined that the benefits of LABAs in improving asthma symptoms outweigh the potential risks when used appropriately with an asthma controller medication in patients who need the addition of LABAs. FDA believes the safety measures recommended above will improve the safe use of these drugs.
Additional Information for Patients
Long-Acting Beta Agonists (LABAs) do not relieve sudden-onset asthma symptoms. Patients should always have a rescue inhaler, such as an albuterol inhaler, to treat sudden onset asthma symptoms.
LABAs must never be taken alone for the treatment of asthma.
Patients who need a LABA plus an asthma controller medication that is not available as a combination product should work with their healthcare professionals to ensure that each individual medication is taken correctly.
Patients should read the Medication Guide for LABAs.
Patients should talk with their healthcare professional to learn the warning signs of worsening asthma.
Patients should discuss any questions they have about the use of LABAs with their healthcare professional.
Additional Information for Healthcare Professionals
Long-Acting Beta Agonists (LABAs) should not be started in patients with acutely deteriorating asthma.
Discuss with patients and families the warning signs of worsening asthma and advise them to seek immediate medical attention should their condition deteriorate.
LABAs do not relieve sudden-onset asthma symptoms. A rescue inhaler, such as an albuterol inhaler, should be prescribed to treat sudden asthma symptoms.
Encourage patients, families, and caregivers to read the Medication Guide that accompanies LABA prescriptions.
When possible, prescribe a combination inhaled corticosteroid – LABA product to pediatric and adolescent patients who need the addition of a LABA for better control of their asthma. Using a combination product will help ensure compliance with both of these medications.